I didn't have any problems with MySql using version 1.5.4 when I set up the site with WebMatrix.
To get pretty URLs, I added this web.config. The top two test links on the general administration page don't work for some reason, but the actual pages do.
I configured email to route via SMTP through sendgrid.
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April 20, 2021: Q2A 1.8.6 released!